Flavay is clinically proven to restore circulation, lessen impaired venous backflow, seal leaky capillaries and prevent outflow of blood or liquid.

Improve Circulation with Flavay

Strengthen Veins and Arteries

Varicoses veins are enlarged, bulging and twisted with warped weak valves, thin vein walls, irregular blood flow, and result in edema, swollen legs, ankles and feet. Healthy veins provide good circulation to heart, regular blood flow with normal vein walls and valves.
Flavay® is clinically proven to restore circulation, lessen impaired venous backflow, seal leaky capillaries and prevent outflow of blood or liquid. (44-48,249,250)

Stronger, Flexible Vessels
Keep Blood Flowing

Healthy Veins and Arteries are Absolutely
Essential for Good Health

Strong, healthy veins return blood to our heart—in direction only—back to our heart. But when veins become weak, brittle and thin, gravity pulls blood backwards so it pools and causes veins to enlarge, bulge and twist. The backflow of blood becomes acidic from accumulation of metabolic waste and causes an intense inflammatory reaction which results in varicose veins, pain, fatigue, itching, burning, swelling, cramping, restlessness and throbbing, and can lead to even more serious circulatory problems, including chronic venous insufficiency (CVI).

Flavay® Strengthens Vessel Walls and Improves Blood Flow in Clinical Trials

Licensed and sold for vascular health in France since 1950, the vascular protective activity of Flavay® has been established by many significant studies.

Flavay® is shown to increase capillary resistance, decrease capillary permeability, and increase rate of lymph flow. (47,48,82,205)

Research shows Flavay® improves strength and tone of veins, arteries, capillaries (the smallest vessels) and lymphoid tissues by strengthening the essential constituents in vascular walls (collagen and elastin). (47,48,82,205)

Flavay® reduces damaging effects of elastase, collagenase and hyaluronidase by altering membrane receptor conformation of vascular walls and preventing destructive enzymes from attaching to and degrading vascular walls. (23,67,268)

Flavay® further prevents destruction of vascular walls by preventing the attachment to membranes of histamine, which decreases strength of vessel walls. (35,56,77-79,87,146)

So, Flavay® helps to both prevent and relieve vascular fragility as it strengthens vessels and helps to prevent the root causes of vessel occlusion—effectively reducing the risk of a rupture or hemorrhage.

Flavay® improves strength and tone of veins and arteries by strengthening the essential constituents in vascular walls (collagen and elastin). (47,48,82,205)

69% of those taking Flavay reported
            50% reduction in clinical parameter scores for pain, paresthesias (burning, numbness, tingling, or prickling), nocturnal cramps and edema (swelling).
A double-blind, placebo-controlled study of 92 subjects with chronic venous insufficiency (CVI) demonstrated improved venous function at a daily dose of 300 mg Flavay® for 28 days. 69% of those taking Flavay® reported 50% reduction in clinical parameter scores for pain, paresthesias (burning, numbness, tingling, or prickling), nocturnal cramps and swelling (edema). (48)
Flavay clinical trial of persons with serious venous problems shows 96% experienced improvement in circulation. 41% very good improvement, 28% good improvement, 27% improvement.
A French trial of 78 subjects with serious venous problems found very favorable results using Flavay®. 75 out of 78 (96%) subjects experienced improvement in circulation. (44)

The effectiveness of Flavay® in subjects with structural deformations (varicose veins) was tested against a placebo and Diosmin (a semisynthetic flavonoid). In both cases, Flavay® lessened functional problems during impaired venous back-flow. The researchers noted the importance of recognizing these functional problems before the varicose veins are visible. (46)

A double-blind study of 50 subjects with chronic venous insufficiency found taking 150 mg Flavay® daily for one month had a more rapid and lasting effect on reducing peripheral edema (swelling) than 450 mg daily of Diosmin. (47)

A double-blind, placebo-controlled study of 92 subjects with chronic venous insufficiency demonstrated improved venous function at a daily dose of 300 mg Flavay® for 28 days. 69% of those taking Flavay® reported 50% reduction in clinical parameter scores for pain, paresthesias (burning, numbness, tingling, or prickling), nocturnal cramps and edema (swelling). 75% of those taking Flavay® felt it was effective, compared to 41% of the placebo group. (48)

A multi-center study of 165 subjects with premenstrual symptoms, including breast tenderness, abdominal swelling, and pelvic pain found taking Flavay® resulted in 60% of subjects reporting improvement in, or cessation of, symptoms after initial treatment; when treatment duration doubled, subjects reporting improvement increased to 78%. (205)

A double-blind, randomized, placebo-controlled study of 63 subjects undergoing treatment for lymph-edema resulting from breast cancer surgery found taking Flavay® (600 mg daily for six months) was superior to placebo in improving pain, skin tension, and arm and shoulder movements. (82)

A review of three French double-blind clinical trials concluded that in subjects with chronic venous insufficiency, Flavay® was significantly more helpful than placebo in improving venous function in terms of swelling, pain, paresthesias (burning, numbness, tingling, or prickling) and nocturnal leg cramps. (42,230)

A much larger French study of 4,729 women taking hormone therapy reported that taking Flavay® (300 mg daily for three months) produced significant improvement in venous and lymphatic insufficiency. (59)

In a double-blind, controlled trial of 32 subjects who had undergone facial cosmetic surgery, those given Flavay® for ten days had significantly less swelling than the placebo-treated group. (73)

In a randomized, controlled trial of 50 adults who had sustained sports injuries, those treated with Flavay® had significantly less swelling at the injured site over the next ten days than the placebo group. (88)

In a double-blind placebo controlled trial of 20 subjects with hepatic cirrhosis, supplementation with 300 mg daily of Flavay® significantly reduced capillary fragility. (45)

A French trial of 78 subjects with serious venous problems found very favorable results using Flavay®. 75 out of 78 (96%) subjects experienced improvement in circulation. (44)

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Flavay®, Endothelial Function and the Nitric Oxide Connection

In addition to improved vessel strength, taking Flavay® for vascular health is based on its antioxidant and anticoagulant effects. Flavay® is shown to improve vasodilation and mildly inhibit angiotensin-converting enzyme (ACE) by modulating nitric oxide metabolism in endothelial cells. (292,296)

Nitric oxide is essential for normal blood circulation as it controls the muscular tone of blood vessels and regulates circulation and blood flow. However, excessive amounts of nitric oxide can be deadly to the cardiovascular system and actually contribute to heart disease and strokes, and many other apparently different disorders (such as arthritis, asthma and Alzheimer's disease). So, in order to have good circulatory health, the body must maintain the right balance of nitric oxide—and that's what Flavay® effectively does. (10,239,265,292,296)

Flavay® aids in production of endothelial nitric oxide which helps to dilate blood vessels and causes blood platelets return to their normal smooth condition. (10,239,265,292,296)

Flavay® Normalizes Reactivity
(“Stickiness”) of Blood Platelets

Flavay® reduces platelet aggregation (“sticky blood”) as it aids in production of endothelial nitric oxide which helps to dilate blood vessels and causes blood platelets return to their normal smooth condition. (10,38-54,103,202)

Flavay® Favorably Increases Erythrocyte Deformability

Studies show Flavay® also improves red blood cell membranes so they remain flexible. Red blood cells (erythrocytes) must change shape extensively without rupturing for micro-circulation. Flavay® is found to favorably increase erythrocyte deformability in diabetics—without increasing viscosity (resistance). (70)

Flavay® is shown to improve circulation by improving strength and tone of vessels, (47,48,82,205) by favorably increasing erythrocyte deformability without increasing resistance, (70) by inhibiting peroxidation and platelet aggregation, (49,50,264,277,283,284) and by improving vasodilation and mildly inhibiting angiotensin-converting enzyme (ACE) through modulating endothelial nitric oxide metabolism. (265,292,296,302)
Nitric oxide is as an important signal for intercellular and intracellular communication throughout the body. (14,102,232-236,248)

Nitric oxide is a free radical and an important signaling molecule that turns genes on and off. Nitric oxide is produced by many cells in our body—from endothelial cells on artery walls, to neurons in our brain, to disease-fighting cells of our immune system. (10,265,292,296)

Nitric oxide is essential in fighting infection, killing tumor cells and promoting wound-healing. As long as nitric oxide is produced in the right amount, it’s beneficial to the body. But when nitric oxide is produced in excess, it causes some of the body’s worst free-radical damage. (14,232-236)

Review of Scientific Studies: Actions of Flavay® on Nitric Oxide

Flavay® protects against toxic overproduction of nitric oxide by blocking nitric oxide synthase. Flavay® works to balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. (10,53,265,302)

Flavay® aids in production of endothelial nitric oxide which controls the muscular tone of blood vessels and circulation, smooth blood platelets and healthy blood flow. (10,239,265,292,296)

Flavay® fortifies and protects the nitric-oxide-based communication between brain and immune cells. This is so important for brain functions because a breakdown in the brain-immune dialog leads to neurological damage and many diseases. (14,202-204,232-236)

Our immune system uses nitric oxide as a immuno-transmitter to activate important white blood cells (macrophages) to fight infection, kill tumor cells and promote wound healing. Studies show how Flavay® protects macrophage white blood cells and their disease-fighting activity. (14,103,261,271,301)

Flavay's® nitric oxide activity improves circulation and blood flow in the eyes. Nitric oxide plays a major role in the control of ocular blood flow as a potent endothelium-derived vasodilator. (237-239)

All higher brain functions require a well-balanced release of nitric oxide and Flavay® helps to fortify and protect that balance. Our brain uses nitric oxide as a neurotransmitter as it controls communication between brain cells and is essential in concentration, learning and memory. Flavay® also reduces production of stress hormones and interference with neurotransmitters as it modulates nitric oxide in brain cells. (14,202-204)

Flavay® works to both stimulate normal synthesis of nitric oxide and to inhibit overproduction of nitric oxide. (103)

Flavay® possesses endothelium-dependent-relaxing (EDR) activity in blood vessels by increasing nitric oxide production and stimulates vascular endothelial growth factor, a signaling factor involved in initiation of wound healing. (53,265,274)

Flavay® promotes nitric oxide production by vascular endothelium, inhibits the synthesis of thromboxane in platelets and leukotriene in neutrophils, modulates the synthesis and secretion of lipoproteins, arrests tumor growth, and inhibits carcinogenesis in different models. (10,265,302)

Nitric oxide stimulates collagen synthesis and subsequent healing at wound sites. (312,313)

In addition, the induction of vascular endothelial growth factor (VEGF) is a crucial step in the reepithelialization phase of skin repair. (314,315)

Flavay® appears to stimulate the expression of VEGF in cultured keratinocytes, showing Flavay® supports wound healing. (316,317)

Experiments show Flavay® relaxes sympathomimetic-induced contractions in a concentration-dependent manner. Flavay® also increases nitric oxide (NO) levels, counteracting the vasoconstrictor effects of sympathomimetics. (10,265)

In endothelial cells challenged with reactive nitrogen species, Flavay® protected against vitamin E depletion, potentially protecting vascular endothelium from oxidative stress from reactive nitrogen species such as nitric oxide. (261,301)

Study comparing activity and synthesis of superoxide dismutase (Cu/Zu-SOD) and nitric oxide in the diabetic and non-diabetic cerebellum and cerebral cortex shows: Diabetes significantly decreases synthesis and activity of Cu/Zu-SOD and Flavay® significantly increases synthesis of Cu/Zu-SOD. Diabetes reduces synthesis of nitric oxide and Flavay® elevates levels back to normal. (372)

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A review of 26 clinical studies reveals Flavay® significantly strengthens vessels in the eyes, improves capillary fragility, vascular lesions, microaneurysms and exudates associated with diabetic retinopathy. (71)
Flavay clinical trial found 147 out of 147 experienced improvement in retinopathies linked to inadequate blood supply.
The effects of Flavay® (100 mg per day) were measured on 147 subjects with retinopathy. Flavay® improved all cases of exudations linked to ischemia (inadequate blood supply) linked to a diabetic, ateriosclerotic, inflammatory, degenerative and myopic nature. (69)
Flavay clinical trial found 21 out of 26 experienced overall improvement in persons with retinopathy, capillary fragility microaneurysms exudates and hemorrhages. Capillary fragility (measured with Parrot’s angiosterrometer) improved in 11 persons, condition of the ocular fundus improved in 15
        persons, and overall improvement in 21 persons.
An open study measured the effects of Flavay® on 26 persons with retinopathy and capillary fragility, microaneurysms, exudates and hemorrhages. Capillary fragility (measured with Parrot’s angiosterrometer) improved in 11 persons, condition of the ocular fundus improved in 15 persons, and overall improvement in 21 persons. (250)
diagram of eye shows cornea, lens, macula and retina, leaking blood vessels, macular edema (swelling in macula), blocked central retinal vein.
Flavay® seals leaky capillaries, strengthens vessels and prevents outflow of blood or liquid. The number of microbleedings in retinal tissue is thereby reduced and visual acuity can improve when taking Flavay®. (249,250)

Flavay® is clinically proven to reduce pressure in ophthalmic membranes by preventing abnormal leakage of fluids into the orbital cavity and tissues and thereby slow down progression of retinopathies. (249,250)

In various clinical trials, Flavay® showed significant improvement with various types of retinal degenerations, including macular degeneration, diabetic retinopathy, retinitis pigmentosa, and hemorrhagic and hypertensive retinopathy. (69-72)

In clinical trials, Flavay® is shown to reduce pressure in ophthalmic membranes by preventing abnormal leakage of fluids into the orbital cavity and tissues and thereby slow down progression of retinopathies. Flavay® seals leaky capillaries as it causes strong protein binding which prevents outflow of blood or liquid from leaky capillaries. The number of microbleedings in retinal tissue is reduced and visual acuity can improve. (249,250)

In clinical trials, all persons given Flavay® showed significant improvement with various types of retinal diseases, including macular degeneration, diabetic retinopathy, retinitis pigmentosa, and hemorrhagic and hypertensive retinopathy. (69-72)

A review of 26 case studies reveals Flavay® significantly improved vascular lesions, microaneurysms, and exudates associated with diabetic retinopathy. (71)

The effects of Flavay® (100 mg per day) were measured on 147 subjects with retinopathy. Flavay® improved all cases of exudations linked to ischemia (inadequate blood supply) linked to a diabetic, ateriosclerotic, inflammatory, degenerative and myopic nature. (69)

The effects of Flavay® (150 mg per day) were measured on 30 retinopathy subjects who suffered from microaneurysms, hemorrhages, exudations and neovascularization after capillary hypoxia. Retinal infectional lesions were stabilized in 80% of subjects taking Flavay®. (72)

An open study measured the effects of Flavay® on 26 subjects with retinopathy and capillary fragility, microaneurysms, exudates and hemorrhages. Capillary fragility (measured with Parrot’s angiosterrometer) improved in 11 subjects, condition of the ocular fundus improved in 15 subjects, and overall improvement in 21 subjects was reported. (250)

Flavay: International and U.S. Patents and Clinically Proven

Flavay® is patented as a scavenger of the free radicals that play a major role in the degradation of collagen and in the initiation, duration and breakdown of inflammation and in ischaemia (reduced blood flow).

“[A] method for preventing and fighting the harmful biological effects of free radicals in the organism of warm blooded animals and more especially human beings, namely cerebral involution, hypoxia following atherosclerosis, cardiac or cerebral infarction, tumour promotion, inflammation, ischaemia, alterations of the synovial liquid, collagen degradation, among others.”
—U.S. Patent No. 4,698,360 (1987).

Flavay® strengthens collagen in your vessels
so your blood flows better and your joints hurt less.

For a healthy mind and body

My joints aren't hurting and my back feels better and I'm even able to work better. I'll tell you, I can feel Flavay! —Ms. C.V.*

I have lupus and taking Flavay enables me to move. I'm not able to do without it. I've been taking it for more than a decade and my skin looks younger, in fact people think I'm my kid's sister. —Ms. L.B.*

I just want to say that I love Flavay. When I stop taking it, the pain comes right back. —Mr. Mark H.*

I love your product called Flavay. I feel it does the job! —Mr. Robert B.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

I had a terrible accident where I fell 20 feet and injured my back and it was really bad. Taking Flavay has made me so much better and now I have no back problem whatsoever. I mowed my yard today. I've referred many many people to your products, and it worked for them too. —Mr. Dave T.*

Flavay is a product I cannot stop taking. When I stopped taking it for a couple of weeks, my neuropathy and arthritis pain come raging back. So I started again on Flavay and the pain is almost completely gone. —Ms. Elsa D.*

I started taking Flavay for arthritis pain and I feel so much better! I'm so thrilled! —Ms. Susan S.*

After taking Flavay for just a week, my sister is doing things she couldn’t do before, such as bending over to pick things up off the floor. —Mr. Joe C.*

The puffiness in my legs is so much better. Oh my gosh this Flavay is great! —Ms. Joan G.*

Your Flavay really helps my husband's chronic pain syndrome and we're almost out! Please ship asap! —Ms. S.W.*

I was taking Flavay for pain and mobility. Now I take Flavay as much for the benefits to my skin as for joint pain. —Mr. H.S.*

I can’t even tell you how much I appreciated finding your product Flavay and the incredible results and relief I have gotten from taking it... I skeptically ordered two bottles... And low and behold, it works. I read that I could take more than 2 that some people had to take 4 or 5 at a time, so I did, hoping and praying, and my prayers were answered. To say thank-you is an understatement, and I have been able to stop all other pain meds. I honestly was on a one way road to nowhere, now I am free again..a feeling I haven’t had in over 12 years. Thank-you!!!!!!!!!!!!!!! —Ms. Beth B.*

I am a nutritionist and I have referred two of my clients to take Flavay. Both of my clients have raved about the product. One of my clients has a problem with circulation and she said Flavay really works for her. —Mr. John H.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

My neighbor is so pleased with Flavay telling me how much better she feels. She has heart problems and taking 2 Flavay per day she has so much energy again and her color is better too. —Ms. C.V.*

I have tried everything else and your Flavay really helps my eyesight. I was having trouble seeing at night and now I don't have that problem anymore. I love Flavay. I also had a blown knee that they had wanted to do surgery on and now I don't have to. I love the Flavay, I really like it! —Ms. T.K.*

I start feeling pain in my joints after a few days of not taking Flavay. —Mr. Mark H.*

My daughter has rheumatoid arthritis in her knees and years ago Flavay had really helped her, so I want to order some more for her. —Ms. K.M.*

For several years I took Flavay for fibromyalgia and it really worked and I felt so much better. Now I need to start again. —Ms. C.H.*

I love your product called Flavay. I feel it does the job! —Mr. R.H.*

I have had joint pain in my hips for a couple years. I have been taking Flavay for about 30 days and I realized I don't have hip joint pain when laying down or sitting for long periods! I will continue to take it daily. —Ms. M.H.*

Thank you so much. I'm desperate!! 😊 Haven't taken them (Flavay and Flavay Plus) for a few months and can tell the difference! —Ms. S.A.*

Since I started taking Flavay I felt so good and I'm hoping to keep getting better. I started taking Flavay for my knee but since I started taking Flavay I've cut way back on asthma meds. The medication affects my brain badly. I want to control asthma instead of it controlling me. Flavay is a big help, I am so happy! —Ms. J.I.*

I began giving my daughter Flavay Plus for ADD and then I decided to add Flavay for my daughter's allergies. I want to tell you, the Flavay works like a charm for my daughter’s allergies. She is 6 years old, and when we ran out of capsules this week she told me, “You've got to get more Flavay!” —Ms. S.S.*

I just wanted to write and say WOW... I was so skeptical of your product at first and really had a negative attitude when I started taking it. I am a 40 yr old female with anxiety, mild ADHD and a host of arthritis and inflammation issues. It was a struggle for me to get out of bed everyday and focus on what needed to be done. I had no focus, no attention span, no energy, and no desire to do anything. About a week into taking Flavay and Flavay Plus, I started noticing that I could think a little clearer. My rheumatoid arthritis flare-ups weren't so bad, though I still have them. feeling better, and having more energy. I never thought I would feel like my old self again. I don't know exactly how you do it,...but this stuff works! I am telling all of my friends to try it because you've given me my old life back! Thank you! —Ms. L.A.*

I am not one to review products, but i can't deny some of the benefits i've experienced using both your biomor curcumin and flavay products. I've been taking both for a few months now, and the two major benefits i've noticed are 1) joint strength and mobility (for workouts) as i am lifting much heavier weights without injury 2) I am a paroxsymal Afib sufferer, and my episodes have gone from 2-3 per week down to zero (most weeks). This can't just be a coincidence. I think there is definitely something in your formulas that stop inflammation and get your body in balance and healing itself. —Mr. B.V.W.*

* Results vary by person and are not guaranteed. NOTE: We do not compensate for our endorsements and testimonials. We do not consider paid testimonials to be nearly as valuable as comments from customers who were not compensated and yet liked the products so much they gave their testimonials anyway.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.