Flavay: International and U.S. Patents and Clinically Proven

Flavay is the Protector Antioxidant

Patented Free Radical Scavenger

Flavay® Significantly Increases Serum Total Antioxidant Protection

two apple slices, one is beautiful and undamaged by oxidation and the other is ugly and damaged by oxidation.
The corrosive and destructive forces that constantly work to break down biological cells are “free radical” molecules. These “radical” molecules are implicated in nearly every known disease, from arthritis to cognitive disorders to cardiovascular disease to cataracts to the aging process itself. (7,14,346-351,355,356)
Free radicals attack and destroy cells and their DNA. Diagram shows free radical steals an electron from DNA and thereby damages DNA.
Every day about 10,000 free radicals attack each cell in our bodies—and they damage anything and everything in the human cell.
Flavay Improves Endogenous Antioxidant Enzyme Activity. Flavay is shown to boost and protect intracelluar antioxidant activities of vitamins C and E, catalast, superoxide dismutase (SOD) and glutathione peroxidase (GPx) Chart shows Nucleus and DNA: vitamin E; Mitochondria: vitamin E and SOD and GPX; Lysosome: vitamins C and E and beta-carotene (vitamin A); Peroxisomes: catalase and GPx; Endoplasmic Reticulum: vitamin E and beta-carotene (vitamin A); Cytoplasm: vitamin C and SOD and GPx; Cell Membrane: vitamin E and beta-caroten (vitamin A); Nuclear Membrane: vitamin E and beta-carotene (vitamin A).
Antioxidants work as a network (not independently) inside the cells and human clinical studies show taking Flavay® significantly increases serum total antioxidant activity in cells. Flavay® is shown to improve the dynamic interplay among the key antioxidants which work together to strengthen and protect cells from free radical damage.(10,33,370)
Free radicals damage DNA. Diagram shows free radical steals an electron from DNA and thereby damages DNA.
The hydroxyl-radical is most dangerous because it can directly attack our DNA. When a free radical steals an electron from DNA in a cell, the cell will die, or lose its ability to replicate, or replicate abnormally (mutation). (7,14,346-351)
Flavay protects DNA from free radical damage. Flavay neutralizes both superoxide and hydroxyl-radicals.
Flavay® protects DNA by neutralizing the hydroxyl-radical and superoxide (superoxide promotes hydroxyl-radical formation). Flavay® is one of the very few antioxidants that can neutralize all varieties of free radicals containing oxygen. The reactive oxygen species are the most energetic and most vicious free radicals. (33,83,274,301,357,360)
Flavay plus a free radical equals a stabilized molecule. Flavay is a radical scavenger and rich electron donor. Free radical is a molecule with a missing electron. Stabilized molecule is now stable because its missing electron is restored. Diagram shows Flavay donating an electron to a free radical to create a stabilized molecule from the free radical.
Flavay® is an electron-rich donor with more reactive sites for neutralizing free-radicals than other antioxidants. Flavay® scavenges a larger quantity and a broader variety of free radicals, transforming free radicals into stable molecules. (1-3,33,271,272,276,282,299)
Flavay regenerates the network antioxidant capacity of vitamins C and E. Flavay is a radical-scavenger with 8 active sites. Vitamin C has 1 active site. Vitamin E has 2 active sites. Diagram shows Flavay donating an electron to vitamin C which then may donate an electron to vitamin E.
Flavay® also donates electrons to the body's endogenous antioxidant network as it regenerates (actually recycles) vitamins C and E. Studies show taking Flavay® increases intracellular antioxidant activities in vitamin C and E, catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPx). (33,83,274,369,371) Flavay® also increases intracellular antioxidant activity of vitamin A. (63,64,71)
Antioxidant and Anti-inflammatory Actions of Flavay. Recycles and improves activities of vitamin C, and protective effects of vitamin E and activity of vitamin A. Protects against lipid peroxidation damage. Highly reactive in both lipid (fat) and aqueous (water) phases of oxidation. Helps balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. Improves total antioxidant capacity and stimulates antioxidant defense systems. Superior antioxidant activity and DNA protection in studies comparing against vitamins C, E and beta carotene (vitamin A).

Antioxidant and Anti-inflammatory Actions of Flavay®

  • Regenerates (actually recycles) and improves intracellular activity of vitamin C and protective effects of vitamin E and activity of vitamin A. (83,33,274,276,63,64,71)
  • Protects against lipid peroxidation damage. Highly reactive in both lipid (fat) and aqueous (water) phases of oxidation. (277,283,284,299)
  • Helps balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. (239,265,292,296)
  • Improves total antioxidant capacity and stimulates antioxidant defense systems. (33,83,274,276)
  • Superior antioxidant activity and DNA protection in studies comparing against vitamins C, E and beta carotene (vitamin A). (272)
  • Helps increase synthesis of and intracellular levels of superoxide dismutase (Cu/Zn-SOD). (369,371,372,373)
  • Helps raise intracellular levels of glutathione peroxidase (GPx) including acetylcysteine and improves glutathione reductase activity. (Flavay® is found to improve intracellular glutathione status better than taking a glutathione supplement. Acetylcysteine is a precursor of glutathione in the body.) (361,366,368,369,371,373)
  • Protects against free radical release of histamine from mast cells. (35,56,78,146)
  • Inhibits pro-inflammatory cytokine actions. (18,25,61,74,81)
Flavay: International and U.S. Patents and Clinically Proven

Flavay® is patented as a scavenger of the free radicals that play a major role in the degradation of collagen and in the initiation, duration and breakdown of inflammation and in ischaemia (reduced blood flow).

“[A] method for preventing and fighting the harmful biological effects of free radicals in the organism of warm blooded animals and more especially human beings, namely cerebral involution, hypoxia following atherosclerosis, cardiac or cerebral infarction, tumour promotion, inflammation, ischaemia, alterations of the synovial liquid, collagen degradation, among others.”
—U.S. Patent No. 4,698,360 (1987).
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Free Radicals and Inflammation

Inflammation is caused by the overproduction of free radicals in a specific area of the body. The inflammatory response is a factor in arthritis, an umbrella term for more than 100 different diseases that produce either inflammation of the connective tissue (joints and tendons) or degeneration of the articular cartilage (a wearing down of the protective covering that cushions the end of bones, allowing bones to rub together without causing damage to the joints). (7,10)

Flavay® decreases inflammation by preventing free radically-induced release and synthesis of compounds that promote inflammation, including histamine, serine proteases, prostaglandins and leukotrienes. (18,25,61,74,81)

Anti-inflammatory activity of Flavay: Flavay protects against unfavorable free-radical release of histamine. Cycle shows: 1 Free radical activator. 2 Flavay protects inactive hyaluronidase. 3 results in reduction of hyaluronidase activation. 4 which protects inactive histamine. 5 which reduces histamine activation. 6. which reduces inflammation and allergic response.

By protecting inert hyaluronidase enzymes from activation by free radicals, Flavay® lowers the inflammatory and allergic activity of histamine. (Hyaluronidase activation also breaks down the hyaluronic acid in connective tissue.) Researchers noted Flavay® has both anti-inflammatory and anti-allergic activity. (3,35,56,78,146)

Flavay® selectively binds to collagen in connective tissue of joints, preventing inflammation and lessening pain. (18,25,61,74,81)

A six-month double-blind, randomized, placebo-controlled study of women recovering from breast surgery found Flavay® improved pain, skin tension and flexibility in movement. (82)

Inflammation-produced enzymes break down collagen and cause over-crosslinking.

Free Radicals, Over-Crosslinking and Collagen

One of the clearest manifestations of free radical damage is over-crosslinking, which is where free radicals reactions cause proteins and/or DNA molecules to fuse together. Over-crosslinking damages proteins (including collagen), enzymes, DNA and RNA. (9)

Over-crosslinking makes collagen inflexible and non-functional and contributes to degeneration and accompanying diseases. (4,14,346-351)

Flavay® binds to collagen fibers and realigns them to a more youthful form. (18,19)

  • In skin cells, over-crosslinking causes saggy skin and wrinkles.
  • Over-crosslinking makes vessels brittle and leaky, causing inflammation, swelling and poor blood flow.
  • In arterial cells, over-crosslinking reduces flexibility which raises blood pressure and puts extra strain on the heart as it pumps harder to maintain a continuous flow of blood.
  • Over-crosslinking causes connective tissue to become stiff, swollen and painful.
  • In the brain, over-crosslinking impedes message transmission between nerve cells so thinking processes slow down and cause concentration and memory problems. (4,14,346-351)

Through synergistic action with vitamin C, Flavay® strengthens and rebuilds the body’s natural collagen proteins and has the remarkable ability to reactivate collagen and elastin. Research demonstrates Flavay® binds to collagen fibers and realigns them to a more youthful, undamaged form. (Pure vitamin C is less effective in synthesis of collagen when the phytonutrients of Flavay® are missing. The same research also established that common bioflavonoids are completely inactive in this respect.) (18,19,23,60,266-268)

too much crosslinking in collagen polypeptides causes leaky vessels and saggy skin
Flavay® improves the beneficial crosslinking between amino acids of the fibers that give collagen its flexibility and strength while preventing the undesirable over-crosslinking that weakens collagen. Laboratory tests demonstrate Flavay’s® ability to reduce degradation of elastin fibers by up to 70%. (18,19)

Flavay® scavenges the free radicals which cause over-crosslinking and premature aging by renewing, strengthening and protecting collagen throughout the body. (44-48,69-72,250,270)

Free Radicals and Cardiovascular Function

Free radicals are involved in the progression of heart disease in several different ways. Heart disease begins with the oxidation of LDL (low-density lipoproteins) cholesterol which leads to the formation of plaque in the arteries. If an artery becomes clogged with plaque, the result can be a heart attack (a sudden loss of blood and oxygen to the heart) or a stroke (loss of blood to the brain). Much of the damage that occurs in both heart attacks and strokes is caused by reperfusion injury, the burst of superoxide free radicals that surge in as blood flow resumes. (3,8,10)

Flavay®, Endothelial Function and the Nitric Oxide Connection

Nitric oxide is essential for normal blood circulation as it controls the muscular tone of blood vessels and regulates circulation and blood flow. However, nitric oxide is a free radical and excessive amounts of nitric oxide can be deadly to the cardiovascular system and actually contribute to heart disease and strokes, and many other apparently different disorders (such as arthritis, asthma and Alzheimer's disease). So, in order to have good circulatory health, the body must maintain the right balance of nitric oxide—and that's the role of Flavay®. (10,239,265,292,296)

Flavay® aids in production of endothelial nitric oxide which helps to dilate blood vessels and causes blood platelets return to their normal smooth condition. (10,239,265,292,296)

Flavay® is shown to improve vasodilation and mildly inhibit angiotensin-converting enzyme (ACE) by modulating nitric oxide metabolism in endothelial cells. (292,296)

Flavay® Strengthens Vessels and Improves Blood Flow

Over 65 years of scientific and clinical research establishes that Flavay® strengthens collagen in vascular walls and capillaries and thereby makes the vessels stronger and more elastic. Flavay® is shown to increase capillary resistance, decrease capillary permeability, and increase rate of lymph flow. (47,48,82,205)

Vericoses veins are enlarged, bulging and twisted with warped weak valves, thin vein walls, irregular blood flow, and result in edema, swollen legs, ankles and feet. Healthy veins provide good circulation to heart, regular blood flow with normal vein walls and valves.
Flavay® is clinically proven to strengthen vessels and restore circulation, lessen impaired venous back-flow, seal leaky capillaries and prevent outflow of blood or liquid. (44-48,249,250)
Clinical trials show Flavay® improves circulation by increasing strength and tone of vessels, (47,48,82,205) by favorably improving erythrocyte deformability without increasing resistance, (70) by inhibiting peroxidation and platelet aggregation, (49,50,264,277,283,284) and by improving vasodilation and mildly inhibiting angiotensin-converting enzyme (ACE) through modulating endothelial nitric oxide metabolism. (265,292,296,302)

Free Radicals and Cognitive Function

Free radicals are created when our bodies fight an infection. The immune system's cytokines go to work, sending messages to the brain that cause more white blood cells to mobilize. The more white blood cells the body activates, the more free radicals they produce, like pellets of poison, that go to work to destroy invaders by breaking down the genetic material of bacteria, toxins, and viruses. (14)

Unfortunately, free radicals can interfere with the biological components of our healthy cells in the same way they destroy invaders, literally dismantling the body's essential cellular proteins, fatty cell membranes and DNA. (7,14,346-351)

Some free radicals are beneficial when functioning properly. Nitric oxide and histamine are free radicals which act as neurotransmitters and immuno-transmitters when functioning correctly. In fact, nitric oxide and histamine are now recognized as very important signaling molecules for intercellular and intracellular communication throughout the body. (14,102,232-236,248,352,353,377)

All higher brain functions require a well-balanced release of nitric oxide in the brain. Nitric oxide also plays a major role in the function of the blood-brain barrier, as it consists mainly of microvascular endothelial cells which are regulated by nitric oxide. (202-204,374)

Excessive production of nitric oxide and histamine can cause some of the brain's worst free radical damage and development of neurological diseases. (10,14,202-204,352,353,377,379-384)

Protection of nitric oxide activity by Flavay® is important to brain functions because when nitric oxide is over-produced, a chain reaction begins which causes neurons to break down and destroy surrounding healthy cells. In Alzheimer’s, free radicals attack cell membranes of the hippocampus, the memory region. In Parkinson’s disease, the area of the brain to suffer the most damage is the “substantia nigra,” which produces dopamine, the neurotransmitter responsible for muscle movement and coordination. (14,232-236,240-242)

Flavay® protects against free radical release of histamine and helps balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. (239,265,292,296)

Flavay® helps the body to regulate nitric oxide as it modulates communication between brain cells and is thereby deeply involved in concentration, learning and memory. (14,240-242)

Light, Oxidation and Vision Loss

Due to the exposure to light and oxygen, the oxidative stress burden is higher in the eye than other tissues. Oxidative damage in responsible for macular degeneration, glaucoma, retinal degeneration and retinopathies, and cataracts. Our eyes (which are 80% collagen) rely on specialized aqueous (water) and lipid (fat) barriers for protection. But, our body's antioxidant mechanisms become progressively less effective as we age. (323-327)

Flavay® Protects Retinal Cells From Oxidation

The hallmark of optic neurodegenerative diseases (including retinopathy and glaucoma) is retinal ganglion cell-death. Studies show Flavay® protects oxidative stress-injured retinal ganglion cells by inhibiting apoptosis (cell-death). (257-259,299)

A number of epidemiologic studies have found that persons with age-related eye diseases had significantly lower levels of antioxidants, particularly vitamin C, than did persons who did not develop those eye conditions. Research shows Flavay® increases intracellular levels of vitamin C and E, and enhances the activity of vitamin A in human eyes. Also, Flavay® provides its own powerful antioxidant protection to the eyes and its tiny blood vessels. (1,81,63,64,71,202,260)

UV light induces oxidative stress to the front of the eye (particularly the cornea and lens), and LED “blue” light reaches deeper into the eye where its cumulative oxidative stress can cause damage to the retina. (320-322,326)
diagram of eye shows cornea, lens, macula and retina, leaking blood vessels, macular edema (swelling in macula), blocked central retinal vein.
In human trials, Flavay® is proven to reduce pressure in opthalmic membranes and thereby slow down progression of retinopathies. (249,250)

In clinical trials of persons with various types of retinal degenerations, including macular degeneration, diabetic retinopathy, retinitis pigmentosa, and hemorrhagic and hypertensive retinopathy, all persons taking Flavay® showed significant improvement. (69-72)

Other clinical studies show Flavay® significantly improves (both objectively and subjectively) light-dark vision impairment in persons who work at computer monitors and persons who drive at night. (63,64,65,71,262,263)

Flavay® is found to increase visual acuity in light-dark adaptations and recovery from glare by increasing the rate of rhodopsin regeneration (an important function of vitamin A). (63-65,71,262,263)

Flavay® is your best protection against “blue light” damage to your eyes. Licensed in France for for use in diabetic retinopathy, Flavay® should be part of the daily nutritional regimen of every aging person (most especially every diabetic person).

man looking at computer shows reflection of light in his glasses
Clinical trials found taking Flavay® significantly improved retinal sensitivity and recovery after glare in persons with healthy eyes working at computers. (63-65,71,262,263)

Change the way you grow older by protecting your brain cells and vision for the many years ahead.

Flavay for a healthy mind and body

Customer Reviews

I have lupus and taking Flavay enables me to move. I'm not able to do without it. I've been taking it for more than a decade and my skin looks younger, in fact people think I'm my kid's sister. —Ms. L.B.*

I just want to say that I love Flavay. When I stop taking it, the pain comes right back. —Mr. Mark H.*

I love your product called Flavay. I feel it does the job! —Mr. Robert B.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

I had a terrible accident where I fell 20 feet and injured my back and it really bad. Taking Flavay has made me so much better and now I have no back problem whatsoever. I mowed my yard today. I've referred many many people to your products, and it worked for them too. —Mr. Dave T.*

Flavay is a product I cannot stop taking. When I stopped taking it for a couple of weeks, my neuropathy and arthritis pain come raging back. So I started again on Flavay and the pain is almost completely gone. —Ms. Elsa D.*

I started taking Flavay for arthritis pain and I feel so much better! I'm so thrilled! —Ms. Susan S.*

After taking Flavay for just a week, my sister is doing things she couldn’t do before, such as bending over to pick things up off the floor. —Mr. Joe C.*

Your Flavay really helps my husband's chronic pain syndrome and we're almost out! Please ship asap! —Ms. S.W.*

I was taking Flavay for pain and mobility. Now I take Flavay as much for the benefits to my skin as for joint pain. —Mr. H.S.*

I can’t even tell you how much I appreciated finding your product Flavay and the incredible results and relief I have gotten from taking it... I skeptically ordered two bottles... And low and behold, it works. I read that I could take more than 2 that some people had to take 4 or 5 at a time, so I did, hoping and praying, and my prayers were answered. To say thank-you is an understatement, and I have been able to stop all other pain meds. I honestly was on a one way road to nowhere, now I am free again..a feeling I haven’t had in over 12 years. Thank-you!!!!!!!!!!!!!!! —Ms. Beth B.*

I am a nutritionist and I have referred two of my clients to take Flavay. Both of my clients have raved about the product. One of my clients has a problem with circulation and she said Flavay really works for her. —Mr. John H.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

I have tried everything else and your Flavay really helps my eyesight. I was having trouble seeing at night and now I don't have that problem anymore. I love Flavay. I also had a blown knee that they had wanted to do surgery on and now I don't have to. I love the Flavay, I really like it! —Ms. T.K.*

I start feeling pain in my joints after a few days of not taking Flavay. —Mr. Mark H.*

My daughter has rheumatoid arthritis in her knees and years ago Flavay had really helped her, so I want to order some more for her. —Ms. K.M.*

For several years I took Flavay for fibromyalgia and it really worked and I felt so much better. Now I need to start again. —Ms. C.H.*

I love your product called Flavay. I feel it does the job! —Mr. R.H.*

I have had joint pain in my hips for a couple years. I have been taking Flavay for about 30 days and I realized I don't have hip joint pain when laying down or sitting for long periods! I will continue to take it daily. —Ms. M.H.*

Thank you so much. I'm desperate!! 😊 Haven't taken them (Flavay and Flavay Plus) for a few months and can tell the difference! —Ms. S.A.*

Since I started taking Flavay I felt so good and I'm hoping to keep getting better. I started taking Flavay for my knee but since I started taking Flavay I've cut way back on asthma meds. The medication affects my brain badly. I want to control asthma instead of it controlling me. Flavay is a big help, I am so happy! —Ms. J.I.*

I began giving my daughter Flavay Plus for ADD and then I decided to add Flavay for my daughter's allergies. I want to tell you, the Flavay works like a charm for my daughter’s allergies. She is 6 years old, and when we ran out of capsules this week she told me, “You've got to get more Flavay!” —Ms. S.S.*

I just wanted to write and say WOW... I was so skeptical of your product at first and really had a negative attitude when I started taking it. I am a 40 yr old female with anxiety, mild ADHD and a host of arthritis and inflammation issues. It was a struggle for me to get out of bed everyday and focus on what needed to be done. I had no focus, no attention span, no energy, and no desire to do anything. About a week into taking Flavay and Flavay Plus, I started noticing that I could think a little clearer. My rheumatoid arthritis flare-ups weren't so bad, though I still have them. feeling better, and having more energy. I never thought I would feel like my old self again. I don't know exactly how you do it,...but this stuff works! I am telling all of my friends to try it because you've given me my old life back! Thank you! —Ms. L.A.*

I am not one to review products, but i can't deny some of the benefits i've experienced using both your biomor curcumin and flavay products. I've been taking both for a few months now, and the two major benefits i've noticed are 1) joint strength and mobility (for workouts) as i am lifting much heavier weights without injury 2) I am a paroxsymal Afib sufferer, and my episodes have gone from 2-3 per week down to zero (most weeks). This can't just be a coincidence. I think there is definitely something in your formulas that stop inflammation and get your body in balance and healing itself. —Mr. B.V.W.*

* Results vary by person and are not guaranteed. NOTE: We do not compensate for our endorsements and testimonials. We do not consider paid testimonials to be nearly as valuable as comments from customers who were not compensated and yet liked the products so much they gave their testimonials anyway.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.